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Procedure

Headshot of the Doctor

Robert Moghim MD

Anchor Healthcare

Platelet Poor Plasma (PPP) Injection

Procedure | 1750852865

Platelet-Poor Plasma, or PPP, is a treatment derived from your blood, with most platelets removed. Unlike Platelet-Rich Plasma, or PRP, which concentrates platelets to promote healing, PPP is often discarded when preparing PRP. However, research suggests PPP may have benefits on its own or when combined with PRP for certain inflammatory conditions.

PRP is used for injuries and osteoarthritis due to its growth factors aiding tissue repair. PPP, although less studied, has proteins and anti-inflammatory components potentially supporting healing, alone or with PRP.

To enhance PPP, specific proteins such as IRAP (Interleukin-1 Receptor Antagonist Protein) and A2M (Alpha-2-Macroglobulin) can be extracted. These may protect cartilage and reduce inflammation. PPP is often combined with PRP for comprehensive treatment. If combining, an extra step separates these elements for reintroduction into PRP.

The process is straightforward: a small blood sample is drawn and spun to isolate PPP, which is then injected into the treatment area. Mild soreness might occur, and there's a slight risk of swelling or infection.

Alternatives to PPP include PRP therapy, physical therapy, or steroid injections. PRP has more research backing it and is more commonly used for healing.

Recovery is quick, with minor discomfort for a few days. PRP results take weeks, and PPP effects are under study. PPP might be an option, often combined with PRP to enhance healing factors. Our healthcare team will guide the best approach for your care.

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