An intradiscal regenerative injection using platelet-rich plasma (PRP) or bone marrow aspirate (BMA) is a minimally invasive treatment that promotes healing and reduces pain in patients with disc-related back pain. Intervertebral discs cushion the spine, but over time, they can degenerate or develop small tears, leading to inflammation and discomfort, sometimes referred to as a "leaky disc". This procedure uses regenerative medicine to stimulate the body’s natural healing process and improve disc health.

Using imaging guidance, your interventionalist inserts a thin needle into the affected disc. If PRP is used, a sample of your blood is drawn and processed to concentrate platelets, which contain growth factors that aid tissue repair. If BMA is used, a small amount of bone marrow is collected, usually from the pelvis, and processed to concentrate the regenerative cells. The prepared solution is then injected into the damaged disc to promote healing, reduce inflammation, and potentially slow disc degeneration.

This outpatient procedure allows you to go home the same day. Some patients experience mild soreness for a few days, which usually resolves on its own. Rare complications could involve nerve damage, infection or discitis. Your provider may recommend temporary antibiotics or activity restrictions and a structured rehabilitation plan, typically beginning six weeks post-procedure.

Intradiscal regenerative injections are an option for patients with persistent disc-related pain that has not responded to conservative treatments like physical therapy, injections like steroids or medications. While results vary, research suggests these injections may improve function and reduce pain by enhancing the body’s ability to heal the disc. Talk to your provider team to learn more.