Complex Regional Pain Syndrome Type II (CRPS II) is a chronic pain condition that develops after a confirmed nerve injury, typically in an arm, hand, leg or foot. While CRPS II shares the same symptoms as CRPS I, the key difference is that a specific nerve injury can be identified. Despite this distinction, both conditions present the same clinical challenges, making early diagnosis and treatment essential.

Diagnosis is based on a physical exam and symptom patterns following the Budapest Criteria, with imaging tests like MRIs or bone scans sometimes used to rule out other conditions but not necessary. This is soley a clinical diagnosis.

CRPS II often develops following surgery or a serious accident causing direct nerve trauma. Symptoms typically include severe, persistent pain that far exceeds what would be expected from the initial injury. Additional signs may include changes in skin color, temperature fluctuations, excessive sweating, and heightened sensitivity to touch or movement—many of which meet the Budapest Criteria for diagnosis.

Managing CRPS II requires a multimodal approach. Physical therapy is essential to maintain movement, prevent stiffness, and reduce functional decline. Medications, such as pain relievers, nerve pain medications, and anti-inflammatories, may help control symptoms but often fall short. In most cases, sympathetic nerve blocks, peripheral nerve stimulation, dorsal root or spinal cord stimulation are used to disrupt pain signals and provide relief.

Although there is currently no cure for CRPS II, early and aggressive treatment can improve outcomes and help manage symptoms effectively. Emotional support and counseling can also be beneficial in helping patients cope with the challenges of living with chronic pain.

If you're experiencing persistent pain after a nerve injury, early intervention is key to improving function and quality of life. Talk to our team to find the best treatment plan for you.