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Robert Moghim MD

Anchor Healthcare

Central Sensitization Syndrome

Diagnosis | 1748909478

Central Sensitization Syndrome (CSS) occurs when the brain and spinal cord become overly sensitive to pain signals, leading to chronic pain even after the original cause is gone. The nervous system amplifies normal signals, making touch, movement, or mild pressure feel painful when they normally wouldn’t be.

This condition can be triggered by injuries, infections, or long-term pain conditions, but emotional stress and psychological factors can also play a role. Genetics may make some people more prone to developing CSS. Symptoms often include widespread pain, extreme sensitivity to touch, fatigue, and sleep disturbances.

Managing CSS requires a comprehensive approach, often involving multiple healthcare providers. Common treatments include: - Medications, such as antidepressants and anticonvulsants, to help calm the nervous system and reduce pain sensitivity. - Non-opioid pain relievers to manage symptoms. - Physical therapy with gradual exercises to improve mobility and reduce pain over time. - Cognitive-behavioral therapy (CBT) to help manage negative thoughts and emotional responses to pain.

Once central sensitization sets in, it becomes extremely difficult to treat and may require neuromodulation such as peripheral nerve, spinal cord or dorsal root ganglion stimulation given the location and type of pain expressed. CSS can affect mood, daily activities, and overall well-being, so treating both the physical and emotional aspects is essential.

If you're experiencing persistent, unexplained pain, early treatment can prevent worsening symptoms and improve quality of life. Talk to our team to find the best treatment plan for you.

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